RGX-104 free Acid ( —— )

产品货号. M21011 CAS No. 610318-54-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

RGX-104 free Acid
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

RGX-104 free Acid 是一种有效的肝 X 核激素受体 (LXR) 激动剂。
产品描述

RGX-104 free Acid is an agonist of potent liver-X nuclear hormone receptor (LXR)?.
体外实验

——
体内实验

Animal Model:NOD SCID or RAG mice injected with 1×106 SKOV3 ovarian cancer cells.Dosage:100 mg/kg.Administration:Oral administration daily for about 60 days.Result:Robustly suppressed tumor growth and progression.
同义词

——
通路

Others
靶点

Other Targets
受体

LXRβ
研究领域

Cancer
适应症

Lymphoma; Solid tumours

CAS Number

610318-54-2
分子量

596.08
分子式

C34H33ClF3NO3
纯度

>98% (HPLC)
溶解度

DMSO:130 mg/mL (218.09 mM)
SMILES

C[C@H](CCOc1cccc(CC(=O)O)c1)N(Cc1cccc(C(F)(F)F)c1Cl)CC(c1ccccc1)c1ccccc1
化学全称

——

1.Tavazoie M F Pollack I Tanqueco R et al. LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer[J]. Cell 2018:S0092867417315064.

计算器

产品手册

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